What is a possible effect of carbimazole on pregnancy?

What is a possible effect of carbimazole on pregnancy?

• A. Neonatal thrombocytopenia
• B. Neonatal goitre
• C. Bone marrow suppression
• D. Jaundice

Answer: (B)

Carbimazole is an antithyroid medication commonly used to treat hyperthyroidism. When considering its effects on pregnancy, one of the recognized risks associated with its use is the development of neonatal goitre. This condition can occur due to the transfer of the drug across the placenta, leading to alterations in the thyroid function of the fetus. In pregnant women, the use of carbimazole can inhibit the normal thyroid hormone synthesis in the fetus, which can result in an enlarged thyroid gland (goitre) as the fetal thyroid attempts to compensate for reduced hormone levels. This effect underscores the importance of careful management of hyperthyroidism during pregnancy, as well as the potential implications for fetal thyroid health. Other conditions such as thrombocytopenia, bone marrow suppression, and jaundice, while they may relate to different drugs or conditions during pregnancy, are not the most direct or recognized effects of carbimazole on neonates.

Carbimazole is an antithyroid medication commonly used to treat hyperthyroidism. When considering its effects on pregnancy, one of the recognized risks associated with its use is the development of neonatal goitre. This condition can occur due to the transfer of the drug across the placenta, leading to alterations in the thyroid function of the fetus.

In pregnant women, the use of carbimazole can inhibit the normal thyroid hormone synthesis in the fetus, which can result in an enlarged thyroid gland (goitre) as the fetal thyroid attempts to compensate for reduced hormone levels. This effect underscores the importance of careful management of hyperthyroidism during pregnancy, as well as the potential implications for fetal thyroid health.

Other conditions such as thrombocytopenia, bone marrow suppression, and jaundice, while they may relate to different drugs or conditions during pregnancy, are not the most direct or recognized effects of carbimazole on neonates.